Some health conditions may make you more susceptible to the sideeffects of the drug. Its antifungal activity is an outcome of the accumulation of the membranedisrupting 14. Discontinue use and do not retreat with terconazole if sensitization, irritation, fever, chills or flulike symptoms are reported during use. Terconazole is an antifungal cream and suppository used for treating vaginal yeast infections candida. This medicine works by killing the fungus or yeast and preventing its growth. Based on comparative analyses with placebo and a standard agent, the adverse experiences considered most likely related to terconazole vaginal cream 0. Terconazole reduces vaginal burning, itching, and discharge that may occur with this condition. Download here free healthcaremagic app to ask a doctor. It has a relatively broad spectrum compared to azole compounds but not triazole compounds. Terconazole is an antifungal medication that fights infections caused by fungus. It works by stopping the growth of yeast fungus that causes the infection. Siga a orientacao do seu medico, respeitando sempre os horarios, as doses e a. Several fdaapproved drug labels may be available for terconazole. Genital complaints in general, and burning and itching in.
Empirical formula hill notation c 26 h 31 cl 2 n 5 o 3. Topical imidazole appears to be more effective than nystatin for treating symptomatic vaginal candidiasis in pregnancy. Terconazole vaginal for use in the vagina is used to treat vaginal candida yeast infections. This study is created by ehealthme based on reports of 10 people who take flagyl and terconazole from food and drug administration fda, and is updated regularly. Pharmacology, adverse reactions, warnings and side effects. This medicine is available only with your doctors prescription. Terconazole is a member of a series of imidazoles whose effectiveness appears similar. Testing shows that it is a suitable compound for prophylaxis for those that suffer from. Product is petroleum based, which may damage latex or rubber condoms or diaphragms separate use by 3. It is used to treat yeast infections of the vagina. Terconazole vaginal cream drug information, side effects, faqs. This medication is sometimes prescribed for other uses.
It comes as a lotion or a suppository and disrupts the biosynthesis of fats in a yeast cell. Terconazole ter kon a zole is an antifungal medicine. Anaphylaxis and toxic epidermal necrolysis tens reported. Terconazole vaginal suppositories, 80 mg is not for ophthalmic or oral use. Terconazole is an antifungal drug that is mainly used to treat vaginal yeast infections or vaginal candidiasis. Find medication information including related drug classes, side effects, patient statistics and answers to frequently asked questions. Throw away terconazole that is no longer needed or expired out of date. Look up information on diseases, tests, and procedures. There are no adequate reports or wellcontrolled studies of terconazole in pregnant women.
Terconazole suppresses the growth of various types of yeats and myceliumforming fungi in in vitro conditions. Each suppository contains 80 milligrams mg of terconazole. Before using terconazole, inform your doctor about your current list of medications, over the counter products e. Bula do terconazol, extraida manualmente da bula em pdf da anvisa. Terconazole vaginal cream and suppositories are used to treat vaginal fungal or yeast infections. Childrenuse and dose must be determined by your doctor. Find patient medical information for terconazole vaginal on webmd including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Aidsinfo provides the following drug label solely as an example of the labels available for terconazole.
The exact mechanism of its action is unknown, although it inhibits the action of the enzyme lanosterol 1demethylase of cytochrome p450 of sensitive fungi similar to other azols described above, causing a reduction in the amount of ergosterin, which is necessary for the organisms. Terconazole vaginal route description and brand names. Adultsone suppository inserted in the vagina once a day at bedtime for 3 consecutive days. Use this medicine terconazole vaginal suppositories as ordered by your doctor. Learn about the reported side effects, related class drugs, and how these medications will affect your daily lifestyle. Draft guidance on terconazole this draft guidance, once finalized, will represent the food and drug administration s fdas current thinking on this topic. Terconazole vetranal, analytical standard sigmaaldrich.
Terconazole vaginal may also be used for purposes not listed in this medication guide. If you have questions about this medicine talk to your doctor, pharmacist, or health care provider. Propylene glycol is the antimicrobi al agent used as a preservative and butylated hydroxyanisole is present as an antioxidant. Find information on terconazole terazol3, terazol7 in daviss drug guide including dosage, side effects, interactions, nursing implications, mechanism of action, half life, administration, and more. Can i use terconazole vaginal cream and fluconazole together. All the information, content and live chat provided on the site is intended to be for informational purposes only, and not a. Terconazole vaginal suppositories, 80 mg are white to offwhite suppositories for intravaginal administration containing 80 mg of the antifungal agent terconazole, cis1p22,4dichlorophenyl2 1 h1,2,4triazol1ylmethyl1,3dioxolan4ylmethoxyphenyl4 isopropylpiperazine, in triglycerides derived from coconut andor palm kernel oil a base of. It is related to several other antifungal drugs including fluconazole, ketoconazole, itraconazole, miconazole micatin, monistat, and clotrimazole lotrimin. The base contained in the suppository formulation may interact with certain rubber or latex products. Fluconazole is prescribed for thrush, candida and fungal infection and is mostly mentioned together with these indications. Do not use terconazole if the original seal over the container opening is broken or missing. Draft guidance on terconazole food and drug administration. It prevents growth of yeast by preventing production of the membranes that surround the yeast cells. In addition, our data suggest that it is taken for yeast infection and itching, although it is not approved for these conditions.
Terconazole is an antifungal drug used to treat vaginal yeast infection. Terconazole is a synthetic triazole derivative structurally related to fluconazole, antifungal terconazole seems to disrupt cell wall synthesis by inhibiting biosynthesis of ergosterol or other sterols, damaging the fungal cell membrane, altering its permeability, and promoting loss of essential intracellular elements. It is not likely that other drugs you take orally or inject will have an effect on terconazole used in the vagina. Inclusion or absence of a drug label on the aidsinfo site does not imply endorsement or lack thereof by aidsinfo. Use as you have been told, even if your signs get better.
Tell each of your healthcare providers about all medicines you use, including prescription and overthe. Terconazole vaginal for use in the vagina is used to treat vaginal candida. Mode of action of terconazole on candida albicans as shown by scanning and transmission electron microscopy during treatment for vulvovaginal candidiasis. Performrepeat microbiological studies koh smear andor cultures in patients not responding to terconazole to rule out other pathogens.
How is this medicine terconazole vaginal suppositories best taken. Terconazole is used to treat fungal and yeast infections of the vagina. Esta bula foi aprovada pela anvisa em 28032016 papel reciclavel ccds v. Drug interactions are reported among people who take flagyl and terconazole together. Terconazole for men doctor answers on healthcaremagic. This is result of inactivation of cytochrome p450dependent 14. Spectrophotometric determination of poorly water soluble drug terconazole. Terazol 3, terazol 7 terconazole side effects, images. Flagyl and terconazole drug interactions ehealthme.